Use and care of animals In biomedical research (94810) - Instructions and Links:

In order to obtain permanent authorization to work with rodents, all students/researchers must successfully perform all the steps required, as detailed here.

IMPORTANT - All steps must be done within the six month period for which the temporary authorization is valid.

STEP A - Lectures and exam

 Filmed lectures:

Please view the course lectures that appear in the following links:

 

Use and care of animals (94810) - Lectures in Hebrew:

Students who will work with animals other than rodents, need to watch only lectures 1 to 7 (including 7).

1. פתיחה
2. סטנדרטיזציה סביבתית וסימנים קליניים 1
3. סטנדרטיזציה סביבתית וסימנים קליניים 2
4. סטנדרטיזציה סביבתית וסימנים קליניים 3
5. סטנדרטיזציה סביבתית וסימנים קליניים 4
6. סטנדרטיזציה גנטית
7. חוקים ונהלים
8. עכברים במעבדה
9. חולדות במעבדה
10. ארנבות ושרקנים במעבדה
11. טכניקות מעבדה

Care and Use of Animals (94810) - ENGLISH LECTURES:

Students who will work with animals other than rodents, need to watch only lectures 1 to 7 (including 7).

1. Basics
2. Environmental Standardization and Clinical Signs 1
3. Environmental Standardization and Clinical Signs 2
4. Environmental Standardization and Clinical Signs 3
5. Environmental Standardization and Clinical Signs 4
6. Genetic Standardization
7. Laws and Regulations
8. The Laboratory Mouse
9. The Laboratory Rat
10. The Laboratory Rabbits and Guinea Pigs
11. Laboratory Techniques

Theoretical test

After viewing  lectures, you must register for the exam through the Authority's website.

The test will be held 4 times a year. Registration will open two and a half months before each test and will close one week before the test date, or upon reaching the maximum number of examineesfor a given test date.

The test will be held in a large hall, in accordance with Purple Badge directives.

The examinees should arrive at exam hall up to half hour before the start time in order to register and get organized to take the   test. The test lasts one hour (60 minutes).

At the end of the exam, the tests will be transmitted through the University system for evaluation.

Once the exams have been evaluated, the Ethics Coordinator will notify each of the registrants of their test result by email.  Students who do not pass the exam may sign up to take the exam again on the next date.

 

 STEP B - Practical training:

1. This step must be carried out under the close guidance of the lead researcher or an experienced and skilled researcher, who possess permanent authorization, from the laboratory group or another group (appointed by the lead researcher for this purpose).

 

2. The Chief Investigator (or another instructor, if any) is responsible for instructing and training the student in performing the actual procedures in accordance with the accepted methods and emphases, as detailed in the instruction pages and as domonstrated in the videos. Please See Bellow: 

Guidance for practical work:

Lab Animal Practical Sessions - Mice - English

Lab Animal Practical Sessions - Mice - Hebrew

Lab Animal Practical Sessions - Rats - English

Lab Animal Practical Sessions - Rats - Hebrew

Mice Insructional Videos:

 

Mice Instructional Videos: (please click on the name of the required video)

English	#	עברית
Instructions of use of syringe and needle	1	שימוש במחט ומזרק
Injection techniques	2	טכניקות הזרקה
Lifting and transferring mice	3	הרמה והעברה של עכבר
Holding and restraining mice	4	תפיסה וריסון של עכבר
Ear marking and genotyping	5	סימון אוזניים ולקיחת דגימה לג'נוטייפינג
Intra-Peritoneal (IP) injection	6	הזרקה IP
Sub-Cutaneous (SC) injection	7	הזרקה SC
Intravenous (IV) injection into tail vein	8	הזרקה IV לווריד הזנב
Substance administration by a gavage	9	מתן חומר בגאבאז'
Obtaining blood from the tail vein	10	לקיחת דם מקצה הזנב
Obtaining blood from the saphenous vein	11	לקיחת דם מווריד הספנוס
Obtaining blood from the facial vein	12	לקיחת דם מווריד הלחי
Obtaining blood from the heart (terminal)	13	לקיחת דם מהלב - טרמינלי

 

 Rats instructional videos: will be added later.

3. The veterinary staff of the Biological Models Authority is at the disposal of the chief and the trainees, to provide advice or technical assistance required for practical training.

4. The practical training and  practice will continue for several weeks / months ,until the instructor and lead researcher see that the student performs the procedures on their own properly, and are able to successfully pass a practical that includes all the mandatory procedures.

 

 STEP C - Signing the declaration form:

1. At this point, after successfully completing review of the   course lectures, test, and the practical training (as described in the previous section), the lead researcher, the advisor and   the student should fill out and sign the Declaration form.

Please send the competed form by email to the Ethics Coordinator(secethics@savion.huji.ac.il )

2. Along with the declaration form, a confirmation of studies (for Hebrew University students) or a confirmation of payment for the course (for those who are not Hebrew University students), must be attached to the email.

3. Upon receipt of the signed declaration form and the certification (tuition or payment), and after approval of the Chairman of the Ethics Committee, The Ethics Coordinator will issue a permanent authorization certificate to the researcher/student Permanent Admission Certificate. The certificate will be sent by email.

 4. Representatives of the Ethics Committee will perform a sample test of students who obtained authorization (in coordination with the students), in order to check the fitness and quality of their work according to accepted procedures. Students who do not pass the test successfully, will be required to pass a training and undergo further testing In order to renew the authorization. 

 

GOOD LUCK!